Clinical trials are the backbone of medical breakthroughs and the lifeblood for the future of treating diseases like Crohn’s and ulcerative colitis. When I started on my biologic treatment in July 2008 to get my Crohn’s disease under control, there were only two treatment options on the market. Fast forward to 2020, and now there are 12 biologic treatment options for IBD. This is all thanks in part to clinical trials. This piece has been entered in the Patients Have Power Writing Contest run by Clara Health designed to raise awareness about the importance of clinical trials. I am passionate about educating others on this topic with the hopes of raising awareness about the power of breakthrough research.
It’s promising and hopeful to know that as we speak, according to ClinicalTrial.gov, there are thousands of clinical trials geared towards IBD research underway around the world! Despite the pandemic, recruitment and patient enrollment for clinical trials are still underway. While there may be 12 biologic treatment options on the market, there are still so many patients who build up antibodies to every drug they try and have nowhere to turn. The Crohn’s and Colitis Foundation finds one-third of patients do not respond to initial IBD treatments. It’s imperative more options become available for our community not only now, but in the future.
Talk it out with your care team
By communicating with your gastroenterologist, you can learn more about the options available and how to find a clinical trial that is tailored to you and fits your needs. By participating, you can help shape the treatment landscape for the future and have a hand in pioneering innovative therapies. Some patients may shy away from clinical trials, thinking they’d be a guinea pig, while others are desperate to improve their quality of life and weigh the benefits as being greater than the risks. It all comes down to the patient population being better informed of what it’s like to be a clinical trial participant and how safety is paramount.
Understanding the safety measures to protect clinical trial participants
Prior to a clinical trial starting, it’s important to understand there are a lot of hoops to jump through. When it gets to the point where patients like you and me participate, the research process on the new treatment has already been going on for more than a decade. According to Clara Health, first the treatment is tested in lab cells and animal studies. Then, the Food and Drug Administration (FDA) gets involved and must give its stamp of approval for a clinical trial to get underway.
Clinical trial participants can have peace of mind knowing they’ll receive top notch medical attention from start to finish and be observed for any potential safety concerns. Every single potential side effect is documented and shared by the study team so that all participants are aware of any new risks, benefits, or side effects that are discovered during the trial.
When you think of participating in a clinical trial it’s empowering to know you are not only possibly helping yourself, but the entire IBD community. The future of how our disease is managed and treated depends on patients like us to step up to the plate. New treatments and therapies are dependent on us. Treatments can’t be created without us. So often the “what if” looms over our heads as IBD patients, in a negative way. With clinical trials, the “what if” signifies endless possibilities, hope, change, and breakthroughs that could ultimately shift and inspire what the future of care looks like for not only us but future generations who will be up against the beast that is Crohn’s and ulcerative colitis.
The Crohn’s and Colitis Foundation has many resources dedicated to this topic that are sure to put your mind at ease.
To learn more about clinical trials head to Clara Health’s website.